Split Shot arrows proc attack modifiers like Eye of Skadi, which is why Skadi is core on Medusa.

Toggle Split Shot off when last hitting so you do not push the wave, keeping it near your tower.

The standard build maxes Split Shot first, takes Mystic Snake at level 2, then maxes Mana Shield second.

In aggressive lanes max Mystic Snake over Mana Shield for the nuke damage and mana sustain.

High rank games require Medusa to accelerate her farm and fight earlier instead of AFK farming to 30 minutes.

Keep the wave near your tower by only last hitting and pulling, using Mystic Snake to harass without pushing.